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 NFLIS News Minimize

Coming SPRING 2021: DEA announces plans to release a fresh new look for the NFLIS website, including NFLIS-Drug, NFLIS-Tox, and NFLIS-MEC informational pages.

4/30/2021: The Drug Enforcement Administration would like to announce the availability of the NFLIS-Drug 2020 Midyear Report.

Link to PDF of NFLIS-Drug 2020 Midyear Report

2/26/2021: The Drug Enforcement Administration would like to announce the availability of the NFLIS-Drug Snapshot (December 2020).

Link to PDF of NFLIS-Drug Snapshot (December 2020)

1/7/2021: The Drug Enforcement Administration would like to announce the availability of the NFLIS MEC/Tox Brief: Toxicology Testing Practices for Benzodiazepines in the United States.

Link to PDF of NFLIS MEC/Tox Brief: Toxicology Testing Practices for Benzodiazepines in the United States

12/17/2020: The Drug Enforcement Administration would like to announce the availability of the report,  NFLIS-Drug Special Report: Tramadol Reported in NFLIS, 2010–2019.

Link to PDF of NFLIS-Drug Special Report: Tramadol, 2010-2019

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Updated: 4/30/2021

 Frequently Asked Questions Minimize


1. What is the current participation level in the National Forensic Laboratory Information System (NFLIS)?

As stated previously, NFLIS is a program of the U.S. Drug Enforcement Administration’s (DEA) Diversion Control Division that has been in operation since 1997. For over 20 years, NFLIS has systematically collected results of drug chemistry analyses, and other related information, from cases analyzed by State, local, and Federal forensic laboratories (NFLIS-Drug). These laboratories analyze substances secured in law enforcement operations across the country. As of February 2019, NFLIS-Drug includes voluntary participation from 50 State systems and 104 local or municipal laboratories/laboratory systems, representing a total of 283 individual laboratories. The NFLIS program is in the process of expanding the scope of data collection to include public and private toxicology laboratory data on toxicological findings from antemortem and postmortem drug testing (NFLIS-Tox) and medical examiner and coroner office data regarding deaths in which drugs were identified (NFLIS-MEC).

2. Why should I participate in NFLIS?

NFLIS participants provide valuable information about the impact that drugs and substance abuse have on public health. Data from participants allow a greater understanding of drug mortality, novel psychoactive substances, drug frequency trends, levels of drugs involved in cause of death, and laboratory or office methods and practices.

Participants have access to a secured, component-specific section of the NFLIS website that allows use of an interactive data query system (DQS) to generate aggregate data at the State, regional, or national level. This aggregate-level data can then be downloaded in report format. Here is a link to the NFLIS-Drug DQS flyer for more information. As DEA receives more data for NFLIS-Tox and NFLIS-MEC, a similar DQS feature will be developed for these components.

3. Why am I being asked to participate in NFLIS when I already participate in NFLIS-Drug?

If your laboratory conducts toxicology drug testing, DEA invites you to extend your NFLIS participation in the NFLIS-Tox component. DEA will use NFLIS-Drug as a road map for this next journey in the NFLIS expansion and hope that you will join us.

4. Who is eligible to participate in NFLIS?

NFLIS participants are either a drug chemistry laboratory (NFLIS-Drug), toxicology laboratory (NFLIS-Tox), medical examiner, or coroner’s office (NFLIS-MEC), or an organization that includes a combination of the three NFLIS components. To be an eligible drug chemistry laboratory, you must perform analyses on drugs seized by law enforcement officers in the United States. To be an eligible toxicology laboratory, you must perform drug toxicology testing (forensic or clinical toxicology, or both). To be an eligible medical examiner or coroner, you must perform at least one of the following duties: conduct investigations to determine a cause and manner of death; sign death certificates; or determine when autopsies should be done, even if your office sends the deceased to another location for an autopsy.

5. How do I become a NFLIS participant?

To become a NFLIS participant, e-mail and let us know that you are interested in becoming a part of the program. In your e-mail, state which NFLIS components your laboratory or office represents. If your laboratory or office uses a laboratory information management system (LIMS), please include the name of that system in your e mail.

Once we receive your e-mail, a NFLIS staff member will respond to your e-mail and will provide a draft Memorandum of Understanding (MOU) that lists the data elements NFLIS would like to collect. When your organization and the DEA agree on the MOU language, both parties will sign the MOU. Once this is accomplished, a NFLIS staff member will assist your laboratory or office in preparing and sending a test data file to the DEA server to ensure that the reporting process will work properly for your laboratory or office. After the test file is accepted, NFLIS staff will then work with your laboratory or office to develop an automated reporting script for your LIMS or other reporting system to assist with reporting.

6. Why does DEA require a Memorandum of Understanding (MOU) for NFLIS participation?

A MOU is a nonbinding agreement between the DEA and a participating laboratory or office that outlines each party’s responsibilities. DEA’s intent is to fully inform those that choose to voluntarily participate in NFLIS about what the DEA will collect. Before DEA can begin accepting data from your laboratory or office, an MOU must be in place. Once the MOU is signed, NFLIS will work with your laboratory or office to assist with NFLIS reporting.

7. Why does DEA need to know what LIMS I use?

DEA's goal is to make reporting as easy as possible for participating laboratories or offices. NFLIS has worked with many LIMS providers to develop automated reporting routines. If DEA has previously worked with your LIMS provider, DEA can ensure that the appropriate technical representatives are available for your questions. If you use a LIMS that is new for DEA, DEA can initiate conversations with that LIMS provider about developing a reporting script for NFLIS reporting. Alternatively, DEA has also successfully worked with in-house management systems not part of a vendor LIMS to make reporting possible and successful.

8. How often will I submit data?

As a NFLIS participant, DEA asks that your facility provide a set of 10–15 core data items each month. A key goal of NFLIS is to minimize effort for our participants; therefore, DEA will provide support to help leverage data abstraction and automation functions with respect to your information system.

9. Are the data secure?

Yes. Data are housed on DEA’s secure network.

10. Is this a violation of HIPAA?

No, all data will remain confidential and we do not collect any personally identifiable information (PII).

11. Will users be able to tell which data came from my laboratory or office?

No. We will not release any laboratory or office specific data; only aggregate data similar to what is included in the NFLIS-Drug reports found here.

12. What will you do with the data?

The data you provide will allow the DEA to quickly identify and target new and emerging drugs of abuse. It will also provide information for use in drug scheduling actions. As more laboratories or offices participate in NFLIS-Tox and NFLIS-MEC, DEA will be able to report aggregated data in midyear and annual reports similar to those that have been generated by NFLIS-Drug using drug chemistry analyses data submitted by laboratories.

13. Who has access to the data?

Data are stored on a secure DEA network and access is restricted to select staff from the DEA and data management staff from the DEA’s NFLIS contractor. By participating in NFLIS, you will have access to the participant section of the NFLIS website and will be able to use interactive queries to generate an abundance of helpful State, regional, and national data summaries and reports. This interactive query is known as the Data Query System (DQS) and can be found on the website. It is only available to NFLIS participants and select supporting organizations. A NFLIS-Drug DQS already exists for NFLIS-Drug participants. As NFLIS-Tox and NFLIS-MEC grow, a similar DQS will be created for these NFLIS components.

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