Session Idle Alert

You will be logged out in due to inactivity. Please click Ok to extend the session or select Log Out to end the session.

Join NFLIS

Laboratory workers looking at NFLIS website on a laptop

NFLIS actively invites new laboratories to join our growing program. Participating laboratories benefit from access to a comprehensive forensic database, keeping them updated on emerging trends and newly identified substances in near real-time. By reporting data to NFLIS, laboratories enhance the accuracy of our national understanding of drug use and trafficking patterns, thereby aiding policymakers in making informed decisions. By sharing data and insights, participants help create a more unified and effective response to the drug challenges facing our communities. Moreover, NFLIS participation supports the development of best practices and contributes to continuous improvements in forensic science methodologies. We encourage laboratories to consider participating in NFLIS by emailing their interest to: NFLIS@dea.gov.

Overview Data Query System Overview Publications NFLIS Substances Synth-Opioid Network FAQs Contact Us DEA Diversion Website

NFLIS News

  • DOSE: Fluoprazolam (August 2026)

    DOSE: Fluoprazolam (August 2026)

    New benzodiazepine (fluoprazolam or fluloprazolam) identified by the DEA Southwest Laboratory. The sample consisted of approximately 500 grams of yellow powder seized from a tableting clandestine laboratory in California in November 2025. Get the Public Alert.

  • DOSE: 4-Fluoro-3-methyl diethylcathinone (July 2026)

    DOSE: 4-Fluoro-3-methyl diethylcathinone (July 2026)

    An unknown material was submitted to the DEA Special Testing and Research Laboratory through the Unknown Identification Support program. The white chalky rock-like material consisted of nicotinamide, sec-butyl butylone, and an unidentified novel cathinone. The Palm Beach County Sheriff’s Office submitted the sample to the Special Testing and Research Laboratory for unknown assistance in April 2026. Get the Public Alert.

  • New NFLIS Reports: First Time Substance Reports

    New NFLIS Reports: First Time Substance Reports

    NFLIS Reports: First Time Substance Reports are now available for selected substances on the NFLIS Substance List webpage. These reports are generalized, unclassified, single topic, one- or two-page reports designed to rapidly share information on newly identified substances with stakeholders and the public. Visit the NFLIS Substance List to view available reports. New reports will be posted on a regular basis.

  • DOSE: N-Propionitrile 5-Chloro Desmethylbrorphine (June 2026)

    DOSE: N-Propionitrile 5-Chloro Desmethylbrorphine (June 2026)

    An unknown material was submitted to the DEA Special Testing and Research Laboratory through the Unknown Identification Support program. The sample consisted of approximately 275 round, green tablets marked K|8. The sample was purchased in Dallas, Texas in May 2026 and was suspected to contain fentanyl. Get the Public Alert.

  • DOSE: 5-Chloro Desmethyl Chlorphine (May 2026)

    DOSE: 5-Chloro Desmethyl Chlorphine (May 2026)

    An unknown material was submitted to the DEA Special Testing and Research Laboratory through the DEA Overdose Surveillance Exchange (DOSE) program. The sample was a white powder suspected to contain fentanyl which was seized by the Knoxville (TN) Police Department and transferred to DEA in May 2026. It was found to contain 5-chloro desmethyl chlorphine with an estimated 34% purity. Get the Public Alert.

NOTICE: Please note that data within the NFLIS database may be subject to change due to ongoing data maintenance. This maintenance is conducted to ensure the accuracy and integrity of the data. Users may observe changes in historical data as a result of these updates. Users should assess data extracts carefully to take data updates into account. Please contact the program at NFLIS@dea.gov for more information.