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NFLIS-Drug

Over 1.1 million drug items reported in 2024

Established in 1997, the National Forensic Laboratory Information System (NFLIS) is a program of the Drug Enforcement Administration (DEA). The DEA's NFLIS-Drug data collection systematically collects drug identification results and associated information from drug cases submitted to and analyzed by participating Federal, State, and local forensic laboratories with drug chemistry sections. In 2024, a total of 1,111,895 drug items were reported by State and local forensic laboratories in the United States.
NFLIS-TOX

About 28 million toxicology requests were referred to responding toxicology laboratories in 2019

Toxicology laboratories are a vital source for identifying drugs used by the public. Data from toxicology laboratories can serve as an early warning system to alert the public health community and law enforcement of the drugs they may encounter, leading to improved treatment, prevention, and enforcement policies. The addition of toxicology data to NFLIS is vital for helping DEA improve drug scheduling, enhance available drug intelligence, and better engage their public health partners.
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NFLIS-MEC

700,000 death cases were accepted by medical examiner and coroner offices (MECs) in 2021, with over 100,000 of those being overdose cases.

MECs are an important data resource for identifying drugs that are used by the public and are potentially deadly. NFLIS-MEC will help DEA improve drug scheduling, enhance available drug intelligence, and better engage DEA’s public safety and public health partners.
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NOTICE: Please note that data within the NFLIS database may be subject to change due to ongoing data maintenance. This maintenance is conducted to ensure the accuracy and integrity of the data. Users may observe changes in historical data as a result of these updates. Users should assess data extracts carefully to take data updates into account. Please contact the program at NFLIS@dea.gov for more information.

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Forensic Laboratories

Toxicology Laboratories

Medical Examiners and Coroners Offices

DEA Diversion Website Synth-Opioid Network Data Query System Overview NFLIS Substances

NFLIS News

NFLIS-Drug Snapshot (March 2025)

Six new substances that were reported from across the U.S. between January 1, 2025, and March 31, 2025, are highlighted in this Snapshot. Top drugs in selected categories and recent trends for carfentanil, MDMA, and medetomidine are also reported. Get the Snapshot.
NFLIS-Drug Snapshot (December 2024)
Six new substances that were reported from across the U.S. between October 1, 2024, and December 31, 2024, are highlighted in this Snapshot. Top drugs in selected categories and recent trends for ketamine, cocaine, and fentanyl are also reported. Get the Snapshot.
NFLIS-Drug Bulletin (September 2024)

Eighteen new substances that were reported from across the U.S. between January 1, 2024, and September 30, 2024, are highlighted in this special Bulletin. Get the Bulletin.